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How Does Clomid Work?

Clomid is usually given on days 3 to 7 of the menstrual cycle. A follow-up ultrasound to monitor the growth of the follicle is performed on day 12. Once the follicle is approximately 20 mm in size, we typically provide an injection called hCG (human chorionic gonadotropin) in order to induce ovulation.

Why Choose Clomid
for Ovulation Induction?

More than 80% of women will ovulate with this injection. We typically like to use Clomid in 3-4 cycles before we move on to a more aggressive therapy. The typical pregnancy rate with Clomid alone is around 15%.

Clomid Side effects

·  Ovarian enlargement 
·  Hot flashes
·  Abdominal bloating
·  Pain in your side
·  Blurred vision
·  Nausea
·  Dizziness
·  Fatigue
·  Headaches

Clomid in combination with injections (Gonal-F, Follistim or Menapur)

Patients who have previously used several cycles of clomid or Letrozole or have a history of low ovarian reserve, we may elect to use clomid in combination with gonadotropins injections. The combination of medications allows us to stimulate several ovarian follicles at the same time. This typically has a higher pregnancy rate (up to 35%) and the risk or twins is about 25%. When we use the combination of oral medications and injections, we find that we reduce the amount of injections needed while maintaining the higher pregnancy rate.

Why Choose Clomid with Injections?

The injectable medications known as Gonal-F and Follistim are synthetic forms of follicle stimulating hormone. Menapur is a combination of follicle stimulating hormone and Luteinizing Hormone.  The key benefit of these injections is they counteract the side effects of Clomid while increasing the estrogen levels and the number of follicles growing.

How Does Clomid with Injections Work?

The injectable medications known as Gonal-F and Follistim are synthetic forms of Follicle Stimulating Hormone, while Menapur is a combination of Follicle Stimulating Hormone and Luteinizing Hormone. Clomid is initiated on day 3-7, and the injections are added on day 6. A pelvic ultrasound is typically done on day 10 to carefully monitor the size of the follicles. Once the follicles reach maturation, an injection of hCG is given to induce ovulation. We can also combine Clomid with gonadotropins and an intrauterine insemination, which is typically done 24-36 hours after the hCG injection.

Ovulation Medication
Learning Center

Learn more about Letrozole and Clomid. If you have questions we have the anwers.